Memorandum of Understanding of the
European Network for the Diagnostics of "Imported" Viral Diseases (ENIVD)




Through Ebola epidemics in Zaire and Gabon, introduction of West-Nile virus into the Americas, SARS, Chikungunya, and Avian Influenza over the past years, we all became aware that dangerous infections could be imported into Europe in a very short time. Because of such emerging problems and due to the great number of viral pathogens it is necessary to establish a European network of collaboration in this field. The improvement of diagnostics of these "imported" and emerging virus infections is the most important step in detecting the pathogens and dealing with them. Therefore a European collaboration in the area of diagnostics of these virus infections is necessary.
In twentytwo meetings scientists from laboratories working in the field of diagnostics of "imported" viral diseases in Albania, Austria, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, FYROM, Germany, Greece, Hungary, Ireland, Italy, Kosovo, Latvia, Lithuania, Malta, Netherlands, Norway, Poland, Portugal, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, and the United Kingdom have build up a network to improve the diagnostics of "imported" viral infections and have worked out objectives to be addressed in this collaboration:


1. Maintain a network of European laboratories working on diagnostics of "imported", rare and emerging viral infections of European Interest. Provide mutual help in the exchange of diagnostic samples, i.e. sera, viruses, methods, and information in order to improve diagnostics.
2. Identify those viral infections more likely to be imported and co-ordinate the objectives and identify laboratories, capable and willing to perform the rapid diagnostics (<24h) of an acute case, suspected to be infected with a viral haemorrhagic fever.
3. Work out recommendations for standardisation, biosafety requirements and quality control in diagnostics laboratories involved in the diagnostics of such diseases.
4. Identify and operate standard assays according to defined quality control criteria.
5. Optimise limited resources by exchanging reagents, methodologies, and expertise.
6. Encourage regular contact within the network through meetings, exchange and training of personnel in biosafety and new laboratory techniques.
7. Open the network for members of other European laboratories.
8. Organise and co-ordinate international activities with the national or international organisations like ECDC, WHO, and CDC.

For further development and the integration of other European members, the project needs European funding in order to maintain the European network and to improve and standardise diagnostic techniques. This will offer an opportunity for technology transfer within the European community and result in better and more efficient diagnostics in the individual countries. In the long run, this initiative offers a chance of increasing the awareness of responsible medical institutions in each country of the EU regarding the problem of emerging and re-emerging viral diseases. By creating these surveillance activities, we will be able to better recognise and respond to threatening emerging and re-emerging diseases in the future. In supporting this group of experts, it will be possible to initiate a co-ordinated international effort to deal with these problems. This offers the chance for future interventions and an effective and close co-operation with the WHO, and also for the future implementation of proposed activities.

We welcome this collaborative network and we are willing to participate in this "European Network for Imported Virus Diseases". We will support this initiative as much as we can and it would be a pleasure for us to be of assistance in this concerted action.






This declaration was signed by :

(N) = Nominated Laboratories

Representative Institution City / Country
Dr. Stefan Aberle Klinisches Institut für Virologie der Universität Vienna / Austria (N)
Dr. Maria João Alves Instituto Nacional de saúde Dr. Ricardo Jorge Lisbon / Portugal (N)
Prof. Antonios Antoniadis Aristotelian University of Thessaloniki Thessaloniki / Greece (N)
Dr. Tatjana Avšič-Županc University of Lubljana, Medical Faculty Lubljana / Slovenia
Dr. Fausto Baldanti IRCCS fontatione Pavia / Italy
Dr. Christopher Barbara Mater Dei Hospital Valetta / Malta
Dr. Stephan Becker Philips-Universität, Institut für Virologie Marburg / Germany
Dr. Luigi Bertinato Regione del Veneto Venice / Italy
Dr. Silvia Bino Instituti i Shendetit Publik Tirana / Albania
Dr. Golubinka BosevskaInstitute of Public Health Skopje / FYROM
Dr. Bojana Boźović Institute of Virology, Vaccines and Sera Belgrade / Serbia
Dr. Michèle Bouloy Institut Pasteur Paris / France (N)
Dr. David BrownPublic Health Laboratory Service London / United Kingdom (N)
Dr. Núria Busquets MartiCampus de Bellaterra, CReSA Barcelona / Spain
Dr. Maria CapobianchiIstituto Nazionale per le Malattie Infettive Rome / Italy (N)
Dr. Saulius Chaplinskas AIDS Center Vilnius / Lithuania (N)
Dr. Remi Charrel Unite des Virus Emergents Marseille / France
Dr. Pascal Cherpillod University Hospitals of Geneva Geneva / Switzerland (N)
Dr. Jeff ConnellNational University of Ireland Dublin / Ireland
Dr. Juan Garcia Costa C. H. Cristal-Piñor Orense / Spain (N)
Dr. Iva Christova National Center for Infectious & Parasitic Diseases Sofia / Bulgaria
Dr. Christian Drosten Bernhard-Nocht-Institut für Tropenmedizin Hamburg / Germany
Dr. Olivier Engler Spiez Laboratory Spiez / Switzerland
Dr. Ernst-J. FinkeSanitätsakademie der Bundeswehr Munich / Germany
Dr. Anders Fomsgaard Statens Serum Institut Copenhagen / Denmark (N)
Dr. Valeria Ghisetti Amedeo Hospital Turin / Italy
Dr. Irina GolovljovaNational Institute for Health Development Tallinn / Estonia
Dr. Robin GopalPublic Health Laboratory Service London / United Kingdom (N)
Dr. Martin GroschupFriedrich Löffler Institut Insel Riems / Germany
Paul Heyman Research Laboratory for Vector-Borne Diseases Brussels / Belgium (N)
Prof. Mirsada HukićClinical Centre University of Sarajevo Sarajevo / Bosnia and Herzegovina
Dr. Olav HungnesNorwegian Institute Of Public Health Oslo / Norway
Dr. Xhevat JakupiNational Institute of Public Health Prishtina / Kosovo
Dr. Janusz KocikMilitary Institute of Hygiene and Epidemiology Warszawa / Poland
Dr. Marion Koopmans Rijksinstituut vor Volksgezondheid Bilthoven / Netherlands
Dr. Leondios Kostrikis University of Cyprus Nicosia / Cyprus
Dr. Florigio Lista Army Medical and Veterinary Research Center Rome / Italy
Dr. Graham Lloyd Health Protection Agency Salisbury / United Kingdom
Dr. Åke LundkvistKarolinska Institute Stockholm Stockholm / Sweden
Prof. Alemka MarkotićUniversity Hospital for Infectious Diseases
"Dr. Fran Mihaljevic"
Zagreb / Croatia
Dr. Miguel J. Martinez YoldiHospital Clinic y Provincal de Barcelona Barcelona / Spain
Dr. Andreas MentisHellenic Pasteur Institute Athens / Greece
Dr. Hermann MeyerSanitätsakademie der Bundeswehr Munich / Germany
Dr. Loredana Nicoletti Istituto Superiore di Sanitá Rome / Italy
Prof. Matthias Niedrig Robert Koch-Institut Berlin / Germany (N)
Dr. Matthias Opp Laboratoire National de Santé Luxembourg / Luxembourg
Prof. Albert Osterhaus Erasmus University, Dept. of Virology Rotterdam / Netherlands
Dr. Delphine Pannetier Laboratoire P4 Inserm Jean Mérieux Lyon / France
Dr. Baiba Rozentale Infectology Center of Latvia Riga / Latvia (N)
Dr. Detlev Schultze Institut für Klinische Mikrobiologie und Immunologie St. Gallen / Switzerland
Dr. Milanko Sekler Veterinary Institute Kraljevo Kraljevo / Serbia
Dr. Marc Strasser Spiez Laboratory Spiez / Switzerland
Dr. Marek Tomasz SzkodaDepartment of Virology NIH Warszawa / Poland
Dr. Antonio Tenorio Centro Nacional de Microbiologia Majadahonda / Spain (N)
Dr. Hugues TolouInstitut de Médecine Tropicale du service de santé des armées Marseille / France
Prof. Antti Vaheri University of Helsinki, Dept. of Virology Helsinki / Finland (N)
Dr. Frank Vandenbussche CODA-CERVA-VAR Brussels / Belgium
Dr. Jean-Francois Valarcher National Veterinary Institute Uppsala / Sweden
Dr. Christian Vandenvelde Research Laboratory for Vector-Borne Diseases Brussels / Belgium (N)
Dr. Marjan van Esbroeck Instituut voor Tropische Geneeskunde Antwerp / Belgium (N)
Dr. Ildikó Visontai National Centerfor Public Health Budapest / Hungary (N)
Dr. Hana Zelená ZÚ se sídlem v Ostravě Ostrava / Czech Republic

Honorary Members
Dr. Jean-Paul DurandInstitut de Médecine Tropicale du service de santé des armées Marseille / France
Prof. Armindo Filipe Instituto Nacional de saúde Dr. Ricardo Jorge Lisbon / Portugal (Obituary)
Dr. Bernard LeGuenno Institut Pasteur Paris / France
Dr. Graham Lloyd Health Protection Agency
Porton Down/U.K.
Prof. Herbert Schmitz Bernhard-Nocht-Institut für Tropenmedizin Hamburg / Germany
Prof. Guido van der Groen Institute of Tropical Medicine, Dept. of Microbiology Antwerp / Belgium

Former Members
Dr. Jiri BeranPurkyne Military Medical Academy Hradec Králové / Czech Republic
Dr. Blenda Böttiger Statens Serum Institut Copenhagen / Denmark
Dr. David CoatesMicrobiological Facilities, DERA Salisbury / United Kingdom
Dr. Vincent Deubel Institut Pasteur Lyon / France
Dr. Fredrik ElghSwedish Institute of Infectious Disease Control Stockholm / Sweden
Dr. Andrew Falconar London School of Hygiene and Tropical Medicine London / United Kingdom
Dr. Heinz Feldmann Philips-Universität, Institut für Virologie Marburg / Germany
Dr. Marie Claude Georges Institut Pasteur Lyon / France
Dr. Jan Groen Erasmus University, Dept. of Virology Rotterdam / Netherlands
Prof. William W. HallNational University of Ireland Dublin / Ireland
Dr. Susan Fisher-Hoch Fondation Mérieux Lyon / France
Dr. Valerija Kilciauskiene Center for Communicable Diseases; Prevention and Control Vilnius / Lithuania
Dr. Milan LabudaInstitute of Virology, Slovak Academy of Sciences Bratislava / Slovakia (Obituary)
Dr. Bernadette Murgue Institut Pasteur Paris / France
Prof. Bo Niklasson Swedish Institute of Infectious Disease Control Stockholm / Sweden
Dr. David Pulford DSTL Salisbury / United Kingdom
Prof. Günter Siegl Institut für Klinische Mikrobiologie und Immunologie St. Gallen / Switzerland
Dr. Hervé Zeller Institut Pasteur Paris / France

Updated: 20 January 12